Darren Aronofsky, director of Requiem for a Dream and Pi, as quoted here  :
[interviewer]: You know, a lot of filmmakers seem to be either very literary-based or else very movie-based who just watch movies. You seem to really be developing this new visual style that suits each story. You know, how did you find this third road?
DA: It's probably because I'm Godless. And so I've had to make my God, and my God is narrative filmmaking, which is -- ultimately what my God becomes, which is what my mantra becomes, is the theme.
Some elaboration on Aronofsky's views, from an interview on The Fountain :
What’s your take on God? Are you religious? Do you believe in God?
DA: I think the themes of The Fountain, about this endless cycle of energy and matter, tracing back to the Big Bang... The Big Bang happened, and all this star matter turned into stars, and stars turned into planets, and planets turned into life. We’re all just borrowing this matter and energy for a little bit, while we’re here, until it goes back into everything else, and that connects us all. The cynics out there laugh at this crap, but it’s true. [Laughs] The messed up thing is how distracted we are and disconnected from that connection, and the result of it is what we’re doing to this planet and to ourselves. We’re just completely killing each other and killing the planet, and it’s a state of emergency right now, I think. All of my charity work has always been about the environment. There are 15,000 species on the endangered species list. Mercury poisoning is my new thing. [Laughs] We’re doing it to ourselves. The fact that there’s mercury poisoning in the breast milk of indigenous people in the North Arctic is all coming from us, and Alzheimer’s is on the rise. What are we doing to ourselves? It’s a complete disconnect. To me, that’s where the spirituality is. Whatever you want to call that connection -- some people would use that term God. That, to me, is what I think is holy.